Endocrine Abstracts

Introduction: Osteoporosis is a frequent complication associated with primary hyperparathyroidism (PHPT), and surgery is the most effective treatment once established. However, many patients are not candidates for it, and different medical options have been investigated. We aimed to assess the efficacy of denosumab (DMAB) in increasing bone mineral density (BMD) and preventing PHPT-related complications.Methods: Case-control study defining cases (Group 1...

Background and aims: Periodontal disease (PD) is a chronic inflammatory condition where the key feature is the alveolar bone loss. Diabetes mellitus is a major risk factor in the occurrence of PD and vitamin D has been found to play a role in the development of diseases such as PD for its immunomoduratory and anti-inflammatory effects. The purpose of this study was to evaluate the relationship between PD and vitamin D levels in type 1 diabetic patients.S...

Background and aims: Primary hyperparathyroidism (PHPT) often presents without classical symptoms such as overt skeletal disease or nephrolithiasis. Treatment strategies have been widely discussed. The objective of our research was to study the effect of parathyroidectomy (PTX) compared to observation (OBS) on skeletal outcomes such as bone mineral density (BMD).Subjects and methods: A retrospective observational study was conducted between 1991 and 2014...

Background and aims: Primary hyperparathyroidism (PHPT) is a common endocrine disorder with different epidemiological patterns among countries. The incidence of PHPT is unknown in Spain. The aim of our study is to assess the prevalence and incidence of diagnosed PHPT in adults between 1970 and 2014 in Santander, a population of 290.000 inhabitants, located in the north of Spain.Subjects and methods: All patients diagnosed with primary hyperparathyroidism...

Introduction: As soon as pregnancy is established, various physiological changes occur in maternal thyroid economy. Due to that, the reference limits of thyroid parameters used for the general population are no longer valid to diagnosis thyroid dysfunction during pregnancy.Methods: We included 266 pregnant women, with no thyroid disorders and resident in Cantabria, a region in northern Spain. They were questioned about iodized salt and iodine supplements...